Mesentery & Impact
I have often been increasingly curious about the ties between excessive edema/swelling & its correlation to other inflammatory illnesses.
Most of us understand the varying chronic physical symptoms associated around inflammation with arthritis, neuropathy, and other illnesses.
Once we rule out all of our possible organ systems- cardiac & kidney, bladder sources of edema. We can then look towards our chronic motility digestive tract issues associated with malnutrition and absorption as logically explained by a lack of protein.
Personal experience allowed my insight into this chronic journey & the queries of possible answers and solutions. Many motility-malabsorption warriors vary so greatly in their chronic journey especially in the area of chronic edema associated with either small intestinal bacterial overgrowth or inflammation from rheumatoid arthritis along with their other multiple diagnoses. Again emphasis on variables in symptoms and severity in the spectrum all vary, as does the responses to protocols use to treat us.
Each of us with multiple diagnoses often have nutritional requirements for one diagnosis which limits our intake options.
An example:
chronic migraines- Cleveland Clinic Foods & Drinks which could trigger migraines
https://my.clevelandclinic.org/health/articles/9648-headaches-and-food
gastroparesis- a great source is available through https://www.iffgd.org/ https://aboutgastroparesis.org/dietary-lifestyle-measures/basic-dietary-guidelines.html
each of us have to find our parameters within our own path of tolerance- solid to liquid is often a variable.
mitochondrial malabsorption (Mito cocktail and limiting sugar as much as possible) to an added layer of lactose intolerance.
I could add diabetes- then you could look at the recommendations for this nutritional success.
Yet, you are seeing how these multiple diagnoses would require a mixture of all the information for each of us to experience our best life. A quality of life and care while seeking cures for chronic communities.
We are advocates doing advocacy over adversity moment by moment. Every aspect of our chronic journey is manageable with knowledge.
Now, we bring in the explanation of the mesentery and all of the questions we are pursuing in regard to digestive tract disorders, disease, issues. As I began my search it became clear there are a lot of doctors working towards this research.
It would be a great contribution for congress to pass HR 3396 to have all of our representatives as cosponsors. We currently have 23 cosponsors. We are deeply appreciative for each of these representatives it is truly beyond words! Thank you for the action you have taken giving hope to millions of lives! We know research is an open door to the answers which will come to all starving for a cure.
https://www.congress.gov/bill/116th-congress/house-bill/3396
H.R.3396 – Functional Gastrointestinal and Motility Disorders Research Enhancement Act of 2019
Mesentery-
Function
The mesentery attaches your intestines to the wall of your abdomen. This keeps your intestines in place, preventing it from collapsing down into your pelvic area.
If the mesentery doesn’t properly form during fetal development, the intestines can collapse or twist. This than lead to blocked blood vessels or tissue death in the abdomen, which are both serious conditions.
Your mesentery also contains lymph nodes. Lymph nodes are small glands that are located throughout your body that help to fight off infections. They contain several types of immune cells and can trap pathogens, such as viruses and bacteria. Lymph nodes in the mesentery can sample bacteria from your intestines and generate an immune response when necessary.
Your mesentery can also produce a protein called C-reactive protein (CRP), which is a sign of inflammation. It’s usually produced in your liver, but fat cells in your mesentery can also produce it.
This new understanding of the mesentery and how it functions could be a game changer for how doctors understand and treat certain conditions. Crohn’s disease is a great example of this.
Crohn’s disease is a type of inflammatory bowel disease that causes inflammation of your digestive tract and bowel tissue. This inflammation can lead to pain, diarrhea, and trouble absorbing nutrients from food.
Connecting the dots for chronic illness for those with motility digestive tract issues along with other autoimmune diseases.
The mesentery of people with Crohn’s disease often has an increase in the amount and thickness of fat tissue. Fat cells in the mesentery can produce proteins that are associated with inflammation, including CRP. A 2016 study linked this fat tissue in the mesenteries of people with Crohn’s disease to increased inflammation, CRP production, and bacterial invasion.
This connection suggests that targeting the mesentery might be an effective treatment option for Crohn’s disease. For example, a probiotic therapy was shown
to improve inflammation-related dysfunction in mesentery tissue samples from people with Crohn’s disease. In addition, removing part of the mesentery may be an effective way to reduce the chance of Crohn’s disease returning after a bowel resection.
The information on the mesentery was taken from https://www.healthline.com/health/mesentery#takeaway
The bottom line
The mesentery is a newly classified organ in your abdomen. Researchers used to think it was made up of several parts, but recent research determined that it’s one continuous structure. This new understanding of the mesentery may help researchers better understand its role in certain conditions, including Crohn’s disease.